Prediction of anti-inflammatory proteins/peptides: an insilico approach

Table 1 Annotation and coverage of MERCI motifs extracted from anti-inflammatory epitopes

S. no.	Motif	Coverage
1.	Hydrophobic hydrophobic tiny F charged	22
2.	Hydrophobic L hydrophobic hydrophobic small polar hydrophobic polar polar	20
3.	Hydrophobic I hydrophobic hydrophobic hydrophobic hydrophobic hydrophobic polar polar	18
4.	Polar L aliphatic hydrophobic positive	17
5.	Hydrophobic aliphatic hydrophobic aliphatic small polar hydrophobic polar polar	17
6.	Hydrophobic hydrophobic small hydrophobic polar hydrophobic polar Q	17
7.	L hydrophobic aliphatic small polar hydrophobic polar polar	16
8.	Hydrophobic polar hydrophobic L polar hydrophobic hydrophobic polar tiny	16
9.	Hydrophobic L polar polar small small hydrophobic hydrophobic	16
10.	Hydrophobic aliphatic polar small hydrophobic charged polar polar hydrophobic	16
11.	Hydrophobic hydrophobic hydrophobic tiny F charged	16
12.	Hydrophobic hydrophobic tiny F charged hydrophobic	16
13.	small aliphatic E N	16

For example “hydrophobic hydrophobic tiny F charged” motif is found in 22 unique anti-inflammatory epitopes

ISSN: 1479-5876