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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Repressed SIRT1/PGC-1α pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration

Fig. 1

Differentiation and characterization of iPSC-RPE. a Immunostaining of the iPSC-RPE cultured on transwells for 4 weeks with ZO-1 antibody, RPE65, Occludin, and Bestrophin. Scale bar represent 100 μM. b Graph illustrating RPE specific gene expressions in differentiated iPSC-RPE cell lines. c RPE specific gene expression in native RPE from which the iPSC-RPE are generated. Relative expression of each gene to GAPDH is compared to its relative expression level in control iPSC-RPE

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Journal of Translational Medicine

ISSN: 1479-5876

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