Table 8 Triacylglycerol metabolism-related pathways activated by daily injection of HPG solution as compared to Sham control
Pathways (p value) | Symbol | Entrez gene name | Fold upregulation |
|---|---|---|---|
Triacylglycerol degradation (0.0158) | FAAH | Fatty acid amide hydrolase | 2.058 |
LIPE | Lipase, hormone-sensitive | 2.014 | |
LPL | Lipoprotein lipase | 4.845 | |
PNPLA3 | Patatin like phospholipase domain containing 3 | 2.602 | |
CDP diacylglycerol biosynthesis I (0.0316) | AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 3.65 |
CDS1 | CDP-diacylglycerol synthase 1 | 2.755 | |
GPAT3 | Glycerol-3-phosphate acyltransferase 3 | 2.103 | |
Phosphotidylglycerol biosynthesis II (non plastidic) (0.0398) | AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 3.65 |
CDS1 | CDP-diacylglycerol synthase 1 | 2.755 | |
GPAT3 | Glycerol-3-phosphate acyltransferase 3 | 2.103 | |
Triacyglycerol biosynthesis (0.0398) | AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 3.65 |
DGAT2 | Diacylglycerol O-acyltransferase 2 | 3.914 | |
GPAT3 | Glycerol-3-phosphate acyltransferase 3 | 2.103 | |
LPIN2 | Lipin 2 | 2.193 |