Fig. 4

Migration assay of human primary neutrophils. Migration assays of human primary neutrophils unstimulated or fMLP (target) stimulated using cell culture inserts. Migrated cells were counted after 0.5 and 1.5 h (n = 4). Neutrophils from AA-genotype carriers showed target-oriented migration already after 0.5 h (a p = 0.029; c p = 0.056). Neutrophils from AC/CC-genotypes did not demonstrate target-oriented migration until 1.5 h, and, when compared to AA-genotype carriers, the number of migrated cells was threefold less than the AC/CC-genotype carriers (b p = 0.029; d p = 0.029)