Table 2 Complete list of ion-channel genes and ion-channel related genes investigated

(A) Amiloride-sensitive cation channel

1

ACCN1

Amiloride-sensitive cation channel 1

2

ACCN2

Amiloride-sensitive cation channel 2

3

ACCN3

Amiloride-sensitive cation channel 3

4

ACCN4

Amiloride-sensitive cation channel 4

(B) Calcium channel, voltage-dependent

5

CACNA1A

Calcium channel, voltage-dependent, P/Q type, alpha 1A Subunit

6

CACNA1B

Calcium channel, voltage-dependent, N type, alpha 1B Subunit

7

CACNA1C

Calcium channel, voltage-dependent, L type, alpha 1C Subunit

8

CACNA1D

Calcium channel, voltage-dependent, L type, alpha 1D Subunit

(C) Cation channel, sperm associated

9

CATSPER1

Cation channel, sperm associated 1

10

CATSPER2

Cation channel, sperm associated 2

11

CATSPER3

Cation channel, sperm associated 3

12

CATSPER4

Cation channel, sperm associated 4

(D) FXYD domain containing ion transport regulator

13

FXYD1

FXYD domain containing ion transport regulator 1

14

FXYD2

FXYD domain containing ion transport regulator 2

15

FXYD3

FXYD domain containing ion transport regulator 3

16

FXYD4

FXYD domain containing ion transport regulator 4

17

FXYD5

FXYD domain containing ion transport regulator 5

(E) Gamma-aminobutyric acid (GABA) A receptor

18

GABRA1

Gamma-aminobutyric acid (GABA) A receptor, alpha 1

19

GABRB3

Gamma-aminobutyric acid (GABA) A receptor, beta 3

20

GABRP

Gamma-aminobutyric acid (GABA) A receptor, Pi

(F) Glutamate receptor, ionotropic

21

GRIA1

Glutamate receptor, ionotropic, AMPA 1

22

GRIN2A

Glutamate receptor, ionotropic, N-methyl d-aspartate 2A

23

HTR3A

5-Hydroxytryptamine (serotonin) receptor 3A, ionotropic

24

HTR3B

5-Hydroxytryptamine (serotonin) receptor 3B, ionotropic

(G) Potassium channel, voltage gated subfamily

25

KCNE3

Potassium channel, voltage gated subfam.E regulatory beta Sub. 3

26

KCNE4

Potassium channel, voltage gated subfam.E regulatory beta Sub. 4

27

KCNH2

Potassium channel, voltage gated Eag related subfamily H, member 2

28

KCNH1

Potassium channel, voltage gated Eag relat.subfam.H, Member 1

29

KCNJ11

Potassium channel, inwardly rectifying subfamily J, member 11

30

KCNJ12

Potassium channel, inwardly rectifying subfamily J, member 12

31

KCNMA1

Potassium channel, calcium activated large conductance subfam.M alpha, member 1

32

KCNMB2

Potassium channel subfamily M regulatory beta subunit 2

33

KCNMB4

Potassium channel subfamily M regulatory beta subunit 4

34

KCNQ1

Potassium channel, voltage gated KQT-Like Subfam. Q, Member 1

35

KCNRG

Potassium channel regulator, protein CLLD4

36

KCNV1

Potassium channel, voltage gated modifier subfamily V, Member 1

37

KCNN1

Potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1

38

KCNN2

Potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2

39

KCNN3

Potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3

40

KCNN4

Potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4

(H) Cholinergic receptor, nicotinic

41

CHRNA1

Cholinergic receptor, nicotinic, alpha 1 (muscle)

42

CHRNA2

Cholinergic receptor, nicotinic, alpha 2 (neuronal)

43

CHRNA3

Cholinergic receptor, nicotinic, alpha 3 (neuronal)

44

CHRNA5

Cholinergic receptor, nicotinic, alpha 5 (neuronal)

(I) Chloride channel

45

CFTR

Cystic fibrosis transmembrane conductance regulator

46

BEST1

Bestrophin 1

47

CLCN1

Chloride channel 1, skeletal muscle (CIC-1)

48

CLCN5

Chloride channel, voltage-sensitive 5 (CIC-5)

49

CLIC1

Chloride intracellular channel 1

50

CLIC4

Chloride intracellular channel 4

(L) Cyclic nucleotide gated channel

51

CNGB3

Cyclic nucleotide gated channel beta 3

(M) Glutamate receptor

52

GRID1

Glutamate receptor, ionotropic, delta 1

53

GRID2

Glutamate receptor, ionotropic, delta 2

(N) Sodium leak channel

54

NALCN

Sodium leak channel, non selective

(O) Purinergic receptor P2X

55

P2RX1

Purinergic receptor P2X, ligand gated ion channel, 1

56

P2RX2

Purinergic receptor P2X, ligand gated ion channel, 2

57

P2RX3

Purinergic receptor P2X, ligand gated ion channel, 3

58

P2RX4

Purinergic receptor P2X, ligand gated ion channel, 4

59

P2RX6

Purinergic receptor P2X, ligand gated ion channel, 6

60

P2RX7

Purinergic receptor P2X, ligand gated ion channel, 7

(P) Sodium-hydrogen exchanger regulatory factor 4

61

PDZD3

PDZ domain containing 3

(Q) Regulatory solute carrier protein

62

RSC1A1

Regulatory solute carrier protein, family 1, member 1

(R) Sodium channel

63

SCN1A

Sodium channel, voltage gated, type I alpha subunit

64

SCN2A

Sodium channel, voltage gated, type II alpha subunit

65

SCN3A

Sodium channel, voltage gated, type III alpha subunit

66

SCN4A

Sodium channel, voltage gated, type IV alpha subunit

67

SCN5A

Sodium channel, voltage gated, type V alpha subunit

68

SCN8A

Sodium channel, voltage gated, type VIII alpha subunit

(S) Glucose activated ion channel

69

SLC5A4

Solute carrier family 5 (glucose activated ion channel)

(T) Two pore segment channel

70

TPCN1

Two pore segment channel 1

71

TPCN2

Two pore segment channel 2

(W) Transient receptor potential cation channel

72

TRPC1

Transient recep. potential cation channel, subfamily C, member 1

73

TRPC2

Transient recep. potential cation channel, subfamily C, member 2

74

TRPC3

Transient recep. potential cation channel, subfamily C, member 3

75

TRPC4

Transient recep. potential cation channel, subfamily C, member 4

76

TRPM1

Transient recep. potential cation channel, subfamily M, member 1

77

TRPM2

Transient recep. potential cation channel, subfamily M, member 2

78

TRPM3

Transient recep. potential cation channel, subfamily M, member 3

79

TRPM4

Transient recep. potential cation channel, subfamily M, member 4

80

TRPM7

Transient recep. potential cation channel, subfamily M, member 7

81

TRPV1

Transient recep. potential cation channel, subfamily V, Member 1

82

TRPV2

Transient recep. potential cation channel, subfamily V, member 2

83

TRPV3

Transient recep. potential cation channel, subfamily V, member 3

84

TRPV4

Transient recep. potential cation channel, subfamily V, member 4

(Y) Zinc activated ion channel

85

ZACN

Zinc activated ligand-gated ion channel

(Z) Acquaporins

86

AQP1

Aquaporin 1

87

AQP2

Aquaporin 2

88

AQP3

Aquaporin 3

89

AQP4

Aquaporin 4

90

AQP5

Aquaporin 5