Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 2 Metabolite ratios with respect to Cr in patients and normal controls from the L-COSY data

From: Non-invasive detection of 2-hydroxyglutarate in IDH-mutated gliomas using two-dimensional localized correlation spectroscopy (2D L-COSY) at 7 Tesla

Metabolites (Cr) Chemical shift Patient 1 Patient 2 Patient 4 Patient 5 Patient 6 Patient 9 Controls (N = 6)
F2 (ppm) F1 (ppm) N/A N/A Grade I Grade I/II Grade II Grade III N/A
NAA-d 2.0 2.0 1.80 1.29 1.49 1.06 1.29 1.21 1.37
Cr-d 3.0 3.0 1.00 1.00 1.00 1.00 1.00 1.00 1.00
Cho-d 3.2 3.2 0.72 0.99 0.86 1.05 0.81 1.81 0.64
mI-d 3.5 3.5 0.36 0.38 0.38 0.68 0.45 0.82 0.28
Lipid-d 0.9 1.3 0.78 1.67 1.09 0.91 0.59 1.25 ND
Lac 4.1 1.3 0.05 0.09 0.14 0.06 0.04 0.10 0.01
Lys 3.0 1.7 0.14 0.12 0.16 0.11 0.12 0.11 0.10
GABA 3.0 1.9 0.10 0.08 0.15 0.11 0.08 0.08 0.07
Glu 2.4 2.0 0.21 0.23 0.21 0.20 0.24 0.19 0.23
Gln 2.5 2.1 0.19 0.39 0.19 0.19 0.21 0.26 0.20
Glx 3.7 2.1 0.09 0.15 0.09 0.11 0.11 0.14 0.17
NAA 4.4 2.5 0.05 0.03 0.04 0.02 0.04 0.03 0.05
Asp 3.9 2.8 0.03 0.04 0.05 0.07 0.05 0.07 0.05
Tau 3.4 3.2 0.14 0.12 0.16 0.12 0.08 0.19 0.09
mI 3.6 3.3 0.23 0.24 0.31 0.30 0.30 0.53 0.24
GPE/PE 3.9 3.2 0.04 0.06 0.04 0.06 0.13 0.11 0.04
2HG 4.0 1.7 ND ND ND ND 0.08 0.10 ND
mI + Cho 4.1 3.3 0.04 0.06 0.04 0.05 0.07 0.08 0.06
PC 4.2 3.6 0.04 0.06 0.06 0.07 0.08 0.12 0.07
GPC 4.3 3.7 0.02 0.05 0.05 0.07 0.07 0.13 0.04
GSH 4.5 2.9 0.03 0.04 0.04 0.07 0.04 0.05 0.03
  1. The first five rows represent data from resonances that appear as diagonal peaks (indicated by -d)
  2. ND not detected