Fig. 2
From: Decoding the usefulness of non-coding RNAs as breast cancer markers
miRNAs and breast cancer metastasis. miRNAs are crucial in metastatic spreading, acting either as oncogenes, typically up-regulated, or as tumor suppressor genes, typically down-regulated. Circulating (red), non-circulating miRNAs and examples of targets. miR microRNA, CD cluster of differentiation, ZEB Zinc Finger E-Box binding homeobox 1, MMPs matrix metalloproteinases, VIM vimentin, CDH1 cadherin 1