Journal of Translational Medicine

Table 1 Physiological characteristics of all study groups of mice

From: Phenotypic and metabolic features of mouse diaphragm and gastrocnemius muscles in chronic lung carcinogenesis: influence of underlying emphysema

	Controls	U	E–U
20 weeks
Initial body weight (g)	18.7 (0.67)	19.4 (1.91)	18.7 (1.55)
Final body weight (g)	26.2 (1.38)	24.5 (2.18)	21.9 (1.50)***,^§
Body weight gain (%)	+39.8 (6.58)	+26.3 (5.46)*	+17.8 (10.8)***
Diaphragm weight (g)	0.08 (0.01)	0.06 (0.004)***	0.06 (0.01)***
Diaphragm (% body weight)	0.30 (0.05)	0.25 (0.02)*	0.26 (0.04)
Gastrocnemius weight (g)	0.15 (0.004)	0.12 (0.01)***	0.12 (0.01)***
Gastrocnemius (% body weight)	0.56 (0.04)	0.50 (0.04)	0.55 (0.05)
35 weeks
Initial body weight (g)	18.7 (0.67)	19.6 (1.61)	18.9 (2.71)
Final body weight (g)	29.4 (2.22)	27.4 (1.41)	22.3 (2.54)***^{, §§}
Body weight gain (%)	+56.9 (10.1)	+39.9 (8.40)*	+18.1 (5.45)***^{, §}
Diaphragm weight (g)	0.09 (0.02)	0.06 (0.01)**	0.06 (0.01)**
Diaphragm (% body weight)	0.30 (0.04)	0.22 (0.04)*	0.28 (0.05)
Gastrocnemius weight (g)	0.15 (0.01)	0.10 (0.02)***	0.10 (0.01)***
Gastrocnemius (% body weight)	0.50 (0.03)	0.37 (0.07)**	0.47 (0.07)^§

Variables are presented as mean (standard deviation)
U urethane, E–U elastase–urethane, g gram
Statistical significance: * p ≤ 0.05, ** p ≤ 0.01 and *** p ≤ 0.001 between any of the experimental groups and the control mice
^§p ≤ 0.05 and ^§§p ≤ 0.01 between urethane and elastase–urethane groups of mice

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ISSN: 1479-5876

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