| |
Controls
|
U
|
E–U
|
|---|
|
20 weeks
|
|
Initial body weight (g)
|
18.7 (0.67)
|
19.4 (1.91)
|
18.7 (1.55)
|
|
Final body weight (g)
|
26.2 (1.38)
|
24.5 (2.18)
|
21.9 (1.50)***,§
|
|
Body weight gain (%)
|
+39.8 (6.58)
|
+26.3 (5.46)*
|
+17.8 (10.8)***
|
|
Diaphragm weight (g)
|
0.08 (0.01)
|
0.06 (0.004)***
|
0.06 (0.01)***
|
|
Diaphragm (% body weight)
|
0.30 (0.05)
|
0.25 (0.02)*
|
0.26 (0.04)
|
|
Gastrocnemius weight (g)
|
0.15 (0.004)
|
0.12 (0.01)***
|
0.12 (0.01)***
|
|
Gastrocnemius (% body weight)
|
0.56 (0.04)
|
0.50 (0.04)
|
0.55 (0.05)
|
|
35 weeks
|
|
Initial body weight (g)
|
18.7 (0.67)
|
19.6 (1.61)
|
18.9 (2.71)
|
|
Final body weight (g)
|
29.4 (2.22)
|
27.4 (1.41)
|
22.3 (2.54)***, §§
|
|
Body weight gain (%)
|
+56.9 (10.1)
|
+39.9 (8.40)*
|
+18.1 (5.45)***, §
|
|
Diaphragm weight (g)
|
0.09 (0.02)
|
0.06 (0.01)**
|
0.06 (0.01)**
|
|
Diaphragm (% body weight)
|
0.30 (0.04)
|
0.22 (0.04)*
|
0.28 (0.05)
|
|
Gastrocnemius weight (g)
|
0.15 (0.01)
|
0.10 (0.02)***
|
0.10 (0.01)***
|
|
Gastrocnemius (% body weight)
|
0.50 (0.03)
|
0.37 (0.07)**
|
0.47 (0.07)§
|
- Variables are presented as mean (standard deviation)
-
U urethane, E–U elastase–urethane, g gram
- Statistical significance: * p ≤ 0.05, ** p ≤ 0.01 and *** p ≤ 0.001 between any of the experimental groups and the control mice
-
§p ≤ 0.05 and §§p ≤ 0.01 between urethane and elastase–urethane groups of mice
