Skip to main content

Table 1 Physiological characteristics of all study groups of mice

From: Phenotypic and metabolic features of mouse diaphragm and gastrocnemius muscles in chronic lung carcinogenesis: influence of underlying emphysema

  Controls U E–U
20 weeks
 Initial body weight (g) 18.7 (0.67) 19.4 (1.91) 18.7 (1.55)
 Final body weight (g) 26.2 (1.38) 24.5 (2.18) 21.9 (1.50)***,§
 Body weight gain (%) +39.8 (6.58) +26.3 (5.46)* +17.8 (10.8)***
 Diaphragm weight (g) 0.08 (0.01) 0.06 (0.004)*** 0.06 (0.01)***
 Diaphragm (% body weight) 0.30 (0.05) 0.25 (0.02)* 0.26 (0.04)
 Gastrocnemius weight (g) 0.15 (0.004) 0.12 (0.01)*** 0.12 (0.01)***
 Gastrocnemius (% body weight) 0.56 (0.04) 0.50 (0.04) 0.55 (0.05)
35 weeks
 Initial body weight (g) 18.7 (0.67) 19.6 (1.61) 18.9 (2.71)
 Final body weight (g) 29.4 (2.22) 27.4 (1.41) 22.3 (2.54)***, §§
 Body weight gain (%) +56.9 (10.1) +39.9 (8.40)* +18.1 (5.45)***, §
 Diaphragm weight (g) 0.09 (0.02) 0.06 (0.01)** 0.06 (0.01)**
 Diaphragm (% body weight) 0.30 (0.04) 0.22 (0.04)* 0.28 (0.05)
 Gastrocnemius weight (g) 0.15 (0.01) 0.10 (0.02)*** 0.10 (0.01)***
 Gastrocnemius (% body weight) 0.50 (0.03) 0.37 (0.07)** 0.47 (0.07)§
  1. Variables are presented as mean (standard deviation)
  2. U urethane, E–U elastase–urethane, g gram
  3. Statistical significance: * p ≤ 0.05, ** p ≤ 0.01 and *** p ≤ 0.001 between any of the experimental groups and the control mice
  4. §p ≤ 0.05 and §§p ≤ 0.01 between urethane and elastase–urethane groups of mice