Fig. 2

The metabolic profiles in the serum. The HFD induced hyperlipidemic rats were treated with or without BC for 4-week, serum was collected, and metabolomics analysis was made by GC/MS. a PCA score plots serum samples from BC treated group and untreated group; b scores plots of PLS-DA between untreated group and BC treated group; c Pearson’s correlations of the quantities of the 35 metabolites determined from serum samples; d heat map showing the fold change (FC) of 19 metabolites. Shades of green represent FC decrease while red represent FC increase; e simplified draft illustrating perturbed pathways involved; f differential metabolites between the groups in glycolysis and citrate cycle; g differential metabolites between groups in glycolysis and citrate cycle; h differential metabolites between the groups in fatty acid biosynthesis. Values were showed as mean peak intensities ± SEM, *P < 0.05, **P < 0.01 and ***P < 0.001, compared with untreated (HFD) group