Fig. 1
From: Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk
MACC1 TMA IHC of patients’ tissue samples. Representative MACC1 IHC show cytoplasmic staining for normal colon tissue (intensity = 1), for two adenomas (intensity = 2), and for two colorectal cancer samples (Cancer 1: intensity = 3 and Cancer 2, intensity = 4). MACC1 protein expression levels were higher in adenoma samples vs. normal tissues (p = 0.004), and were higher in cancer samples vs. normal tissues (p < 0.001). No major differences in MACC1 expression levels were found between adenoma vs. cancer cases or tubular adenomas vs tubulovillous adenomas. Sections treated without the primary antibody served as controls. Images are presented for 20× magnification