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Table 1 Patient characteristics

From: Serum metabolites predict response to angiotensin II receptor blockers in patients with diabetes mellitus

 

Type 2 diabetes discovery cohort (n = 49)

Type 1 diabetes validation cohort (n = 50)

Baseline

 Age (years)

59.0 (10.0)

44.6 (8.9)

 Male sex (number (%))

39 (80)

30 (60)

 SBP (mmHg)

140.0 (15.4)

150.6 (17.7)

 DBP (mmHg)

81.6 (8.8)

84.7 (10.9)

 HbA1c (%)

8.3 (1.4)

8.9 (1.2)

 HbA1c (mmol/mol)

67.2 (15.3)

73.8 (13.1)

 Cholesterol (mmol/l)

5.3 (1.0)

5.2 (1.0)

 HDL (mmol/l)

1.2 (0.3)

1.6 (0.5)

 GFR (ml/min/1.73 m2)

102.3 (19.2)

86.5 (23.4)

 24-h UAE (mg/24 h)

84 [65, 200]

1211 [598, 2023]

Follow-up

 Change in SBP (mmHg)

−6.4 (16.2)

−8.7 (14.3)

 Change in DBP (mmHg)

−6.0 (8.8)

−5.6 (8.6)

 Percent change in UAE (%)

−42 % [−69, −8]

−43 % [−62, −23]

 >30 % decrease in UAE from baseline [number (%)]

31 (63)

34 (68)

 GFR change after response period (mL/min/1.73 m2/year)

Not available

−3.8 (3.6)

  1. Data are reported as mean ± standard deviation (SD) or number (percent) or median [25th, 75th percentile]