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Table 1 Tagging SNPs analysed in PON1

From: Interaction between polyphenols intake and PON1 gene variants on markers of cardiovascular disease: a nutrigenetic observational study

SNP Alleles (minor/major) MAFa Position (bp) Locationb Tagged SNPsc
rs854549 A/C 0.39 94,764,521 3downstream  
rs3735590 A/G 0.05 94,765,431 3downstream rs3917572
rs854551 A/G 0.14 94,765,613 3utr rs854550
rs854552 C/T 0.20 94,765,860 3utr  
rs3917567 C/T 0.04 94,768,021 Intronic rs3917556,rs3917527,rs3917551,rs3917548,rs3917541,rs3917569,rs2158155
rs854555 A/C 0.33 94,768,327 Intronic  
rs3917550 A/G 0.10 94,772,509 Intronic  
rs662 C/T 0.30 94,775,382 Coding rs2057681,rs2269829
rs3917538 A/G 0.24 94,775,829 Intronic  
rs2074354 A/G 0.13 94,778,523 Intronic rs3917577,rs3917586
rs854560 T/A 0.44 94,784,020 Missense rs705378,rs854561
rs3917498 T/G 0.35 94,784,191 Intronic  
rs2074351 A/G 0.30 94,785,735 Intronic  
rs2272365 C/A 0.19 94,786,562 Intronic  
rs854569 T/G 0.14 94,787,991 Intronic  
rs3917477 G/A 0.04 94,789,902 Intronic rs3917476
rs854571 T/C 0.26 94,792,555 5upstream rs854570
rs854572 C/G 0.39 94,792,632 5upstream  
  1. Bp base pair, MAF minor allele frequency
  2. aAllele frequencies were calculated in the studied population sample
  3. bPosition and location were taken from the NCBI build 36 (hg18)
  4. cTagged SNPs present a r2 >0.80 with analyzed PON1 markers