Fig. 6
From: Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus
Polyfunctional CD8+ T cells are induced upon TLR activation in patients with LP. PBMCs obtained from patients with LP (n = 10, black bars) and HCs (n = 19, white bars) were left unstimulated or were stimulated with the TLR agonists CL097/TLR7-8 and SEB for 16 h and assessed by flow cytometry. Cytokine production (TNF, IL-22, IL-17, IL-10 and IFN-γ) by stimulated CD3+CD8+ T cells was subtracted from the baseline levels. The pie chart represents the capacity of T cells to secrete combinations of 5, 4, 3 or 2 cytokines. The results are shown as the mean ± SEM. *P < 0.05, **P < 0.01 when compared with the HC group