Fig. 4
From: Resveratrol increases AdipoR1 and AdipoR2 expression in type 2 diabetic nephropathy
Expression of eNOS, proapoptotic Bax and antiapoptotic Bcl-2 in the renal cortex of db/m and db/db mice with or without resveratrol. Protein lysates (40 μg) from renal cortexes were separated by SDS–PAGE and analyzed by western blot. a Representative results are for phospho-Ser1177 and total-eNOS, Bax, Bcl-2 and β-actin and the quantitative analyses are for the phospho-Ser1177/total-eNOS ratio and Bcl-2/Bax ratio. *p < 0.05 and **p < 0.01 vs. db/m, db/m Res and db/db Res mice mice, respectively. b Representative immunohistochemical staining for TUNEL-positive cells with quantitative analysis. #p < 0.001 vs. db/m, db/m Res and db/db Res mice. eNOS endothelial nitric oxide synthase, Bcl-2 B cell leukemia/lymphoma 2, Bax Bcl-2-associated X protein, Res resveratrol, TUNEL terminal deoxynucleotidyl transferase dUTP nick end labeling