Skip to main content

Table 5 Univariate analysis of the impact of serine/glycine-related protein expression in papillary thyroid carcinoma on disease-free and overall survival by the log-rank test

From: Expression of serine/glycine metabolism-related proteins is different according to the thyroid cancer subtype

Parameter

Number of patientsa/recurrence/death

Disease-free survival

Overall survival

Mean survival (95 % CI) months

p value

Mean survival (95 % CI) months

p value

PHGDH in tumor

0.790

 

0.806

 Negative

126/6/6

105 (101–108)

 

106 (103–109)

 

 Positive

218/12/12

106 (104–109)

 

107 (105–110)

 

PSAT1 in tumor

0.159

 

0.231

 Negative

280/17/13

106 (103–109)

 

108 (106–110)

 

 Positive

64/1/5

108 (105–111)

 

103 (97–108)

 

PSPH in tumor

0.606

 

0.221

 Negative

300/15/14

107 (105–109)

 

108 (106–110)

 

 Positive

44/3/4

103 (96–110)

 

103 (96–109)

 

SHMT1 in tumor

0.498

 

0.248

 Negative

236/11/10

107 (105–110)

 

108 (106–110)

 

 Positive

108/7/8

104 (100–109)

 

105 (101–109)

 

SHMT1 in stroma

0.655

 

0.684

 Negative

212/12/10

106 (103–109)

 

108 (106–110)

 

 Positive

132/6/8

107 (104–111)

 

107 (103–110)

 

GLDC in tumor

0.516

 

0.059

 Negative

285/14/12

107 (105–109)

 

108 (106–110)

 

 Positive

59/4/6

104 (97–110)

 

103 (97–109)

 
  1. CI confidence interval; PHGDH phosphoglycerate dehydrogenase; PSAT phosphoserine aminotransferase; PSPH phosphoserine phosphatase; SHMT serine hydromethyl transferase; GLDC glycine decarboxylase
  2. aCases of anaplastic carcinoma were excluded