Fig. 4

Correlation between the expression of serine/glycine metabolism-related proteins and clinicopathologic factors in papillary carcinoma. a In PTC, PHGDH expression is associated with tumor size, with an increased tumor size in PHGDH-positive cases. b Inflammatory type shows a lower rate of PHGDH expression compared to other subtypes, and desmoplastic type and inflammatory type have a higher rate of tumoral (c) and stromal d SHMT1 expression compared to pauci type and sclerotic type