Fig. 3
From: Longitudinal study of DNA methylation during the first 5 years of life
Distance to centromere (a, b) and telomere (c, d) of differentially methylated probes. a, b Violin plots showing the distribution of the distance to centromeres for the hypermethylated (a) and hypomethylated (b) CpG sites (In) with respect to those sites belonging to the Illumina® 450 k microarray but not included in the corresponding subset of interest (Out). There is no statistically significant relationship between both hyper- and hypomethylated CpG sites and their distance to centromeres. c, d Violin plots showing the distribution of the distance to telomeres for the hypermethylated (c) and hypomethylated (d) CpG sites (In) with respect to those sites belonging to the Illumina® 450 k microarray but not included in the corresponding subset of interest (Out). Only hypomethylated probes have a statistically significant change in their distance to telomeres, but with a minimal effect size (Wilcoxon test; p < 0.001, D = −0.0017)