Fig. 4

Arthritic ApoE^−/− mice have increased levels of collagen. a Picrosirius red-positive tissue sections of arthritic C57BL/6 (control, n = 10) and ApoE^−/− (n = 6) mice. Picrosirius red staining is pseudocolored yellow. b Quantification of picrosirius red staining on tissue sections (2 sections/mouse) described above. Data are represented as mean ± SEM. Asterisk denotes statistically significant differences: ***p < 0.001