Fig. 4

Feasibility of cardiac activation simulation on customized meshes with pre-defined structural abnormalities. Top row depicts the segmentations created using the custom made tool. The middle and right column segmentations have a pre-defined structural abnormality. The impact of these abnormalities is visible on the corresponding simulations. A delayed activation can be observed in the isochrone map for regions with edema (solid black arrows). The computational mesh containing a transmural scar (black arrowheads and dotted black arrows), demonstrates a total conduction block