Table 1 Demographic characteristics of OSA patients and control subjects
| Â | NC (controls) | OSAbaseline (before surgery) | OSAfollow (after surgery) | p value | ||
|---|---|---|---|---|---|---|
NC vs. OSAbaseline | NC vs. OSAfollow | OSAbaseline vs. OSAfollow | ||||
Number | 15 | 21 | Â | Â | Â | Â |
Sex (M:F) | 11:4 | 18:3 | Â | 0.418 | Â | Â |
Age (years) | 39.80 (9.53) | 40.14 (10.80) | Â | 0.922 | Â | Â |
BMI (kg/m2) | 23.97 (2.50) | 26.24 (3.40) | 25.83 (3.73) | 0.050 | 0.130 | 0.033* |
HbA1c (%) | 5.54 (0.25) | 5.80 (0.46) | 5.75 (0.54) | 0.206 | 0.338 | 0.537 |
Sugar (mg/dl) | 92.00 (8.04) | 93.43 (12.14) | 95.05 (12.40) | 0.925 | 0.546 | 0.217 |
hs-CRP (mg/dl) | 0.80 (0.81) | 3.22 (4.30) | 2.32 (2.62) | 0.108 | 0.069 | 0.292 |
Total cholesterol | 192.10 (34.93) | 191.96 (29.98) | 194.57 (32.00) | 0.880 | 0.985 | 0.599 |
Triglyceride | 120.87 (95.78) | 156.13 (107.13) | 154.87 (79.05) | 0.441 | 0.343 | 0.926 |
HDL | 62.67 (14.44) | 54.70 (10.57) | 53.39 (10.32) | 0.085 | 0.056 | 0.393 |
LDL | 106.40 (34.41) | 122.04 (29.46) | 115.04 (39.67) | 0.171 | 0.540 | 0.318 |
Smoking (yes/no) | (14/1) | (18/3) | (19/2) | 0.728 | 1.000 | 1.000 |
Voxel-based morphometry | ||||||
GMV (ml) | 613.32 (49.33) | 620.69 (72.14) | 620.86 (72.69) | 0.707 | 0.702 | 0.953 |
WMV (ml) | 587.49 (59.16) | 583.96 (53.91) | 582.17 (50.92) | 0.851 | 0.722 | 0.373 |
CSFV (ml) | 216.52 (25.02) | 215.96 (22.39) | 216.81 (22.52) | 0.943 | 0.971 | 0.477 |
TIV (ml) | 1417.33 (113.22) | 1420.61 (119.15) | 1419.83 (119.06) | 0.931 | 0.947 | 0.674 |
Polysomnography (PSG) | ||||||
AHI | 2.43 (1.61) | 38.77 (19.91) | 25.21 (20.93) | 0.000* | 0.000* | 0.004* |
De-saturation index | 0.77 (0.82) | 26.59 (19.38) | 16.88 (19.23) | 0.000* | 0.006* | 0.009* |
Average O2 saturation | 97.09 (0.82) | 95.59 (1.39) | 95.81 (1.79) | 0.004* | 0.053 | 0.534 |
Snoring index | 208.96 (240.67) | 385.71 (179.17) | 323.52 (181.58) | 0.059 | 0.278 | 0.116 |
Systolic BP (mmHg) | 124.90 (15.86) | 135.58 (15.38) | 132.07 (11.58) | 0.538 | 0.497 | 0.323 |
Diastolic BP (mmHg) | 75.53 (9.09) | 84.58 (11.00) | 82.55 (12.01) | 0.082 | 0.142 | 0.469 |
Leukocyte apoptosis (%) | ||||||
Granulocyte APO 2.7 apoptosis | 0.429 (0.219) | 0.894 (1.012) | 0.831 (0.940) | 0.160 | 0.125 | 0.830 |
Monocyte APO 2.7 apoptosis | 2.135 (1.410) | 3.156 (3.321) | 2.570 (2.903) | 0.439 | 0.575 | 0.585 |
Lymphocyte APO 2.7 apoptosis | 0.481 (0.226) | 0.658 (0.444) | 0.475 (0.255) | 0.283 | 0.835 | 0.164 |
Total leukocyte APO 2.7 apoptosis | 0.891 (0.426) | 1.442 (1.084) | 1.271 (1.004) | 0.128 | 0.236 | 0.626 |
Granulocyte late apoptosis | 11.726 (6.986) | 16.667 (10.032) | 14.599 (14.039) | 0.107 | 0.331 | 0.622 |
Granulocyte early apoptosis | 13.920 (5.615)) | 23.117 (11.007) | 18.250 (12.008) | 0.010* | 0.302 | 0.099 |
Monocyte late apoptosis | 12.593 (7.401) | 12.480 (8.384) | 14.520 (8.876) | 0.936 | 0.428 | 0.318 |
Monocyte early apoptosis | 15.263 (5.068) | 23.254 (8.033) | 16.796 (8.342) | 0.002* | 0.579 | 0.007* |
Lymphocyte late apoptosis | 2.331 (1.090) | 2.306 (0.915) | 2.577 (1.178) | 0.906 | 0.647 | 0.601 |
Lymphocyte early apoptosis | 5.410 (1.988) | 6.716 (2.505) | 6.600 (2.624) | 0.147 | 0.210 | 0.981 |
Total leukocyte late apoptosis | 6.875 (2.588) | 7.541 (3.170) | 7.972 (4.126) | 0.407 | 0.174 | 0.744 |
Total leukocyte early apoptosis | 9.203 (1.987) | 13.535 (3.713) | 10.599 (4.431) | 0.000* | 0.286 | 0.021* |