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Table 2 PFN2 protein expression during cancer progression by IHC analysis in Han population

From: PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma

Cancer progression

Immunostaining

P value

Low (%)

High (%)

Normal esophageal epitheliumâ‘ 

124 (91.9)

11 (8.1)

â‘ :â‘¡ P < 0.001*; â‘ :â‘¢ P < 0.001*

Low grade intraepithelial neoplasiaâ‘¡

31 (59.6)

21 (40.4)

â‘¡:â‘¢ P < 0.001*; â‘¡:â‘£ P < 0.001*

High grade intraepithelial neoplasiaâ‘¢

3 (9.0)

30 (91.0)

â‘¢:â‘£ P = 0.241

ESCCâ‘£

33 (17.2)

159 (82.8)

â‘ :â‘£ P < 0.001*

  1. * P < 0.05, as determined by Pearson’s χ2 test