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Table 3 Multivariate analysis of the association between prognostic variables and survival in cervical cancer patients

From: Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients

Variables Disease-free survival Overall survival
DFS HR [95 % CI], P value OS HR [95 % CI], P value
FIGO stage (IB2/IIB vs. IB1/IIA) 1.72 [0.86–3.47], 0.090 2.00 [0.70–5.73], 0.190
Cell type (AD vs. SCC) 3.80 [2.10–6.86], <0.001 5.89 [2.37–14.65], <0.001
LN metastasis 4.15 [2.20–7.83], <0.001 2.89 [1.12–7.49], 0.030
Tumor size (>4 cm) 0.96 [0.49–1.88], 0.910 0.90 [0.32–2.54], 0.840
PM involvement 1.31 [0.58–2.94], 0.520 1.72 [0.52–5.69], 0.380
FGFR1+ 0.52 [0.25–1.11], 0.090 0.48 [0.16–1.50], 0.210
FGFR2+ 0.51 [0.27–0.97], 0.040 0.24 [0.07–0.83], 0.020
FGFR3+ 0.56 [0.30–1.03], 0.060 0.29 [0.11–0.78], 0.010
FGFR4+ 0.51 [0.28–0.91], 0.020 0.33 [0.13–0.83], 0.020
FGFR2+/FGFR3+ 0.37 [0.17–0.82], 0.010 0.13 [0.03–0.60], 0.010
FGFR2+/FGFR4+ 0.30 [0.13–0.68], 0.004 0.17 [0.05–0.63], 0.008
FGFR3+/FGFR4+ 0.33 [0.15–0.69], 0.004 0.11 [0.03–0.44], 0.002
FGFR2+/FGFR3+/FGFR4+ 0.24 [1.10–0.60], 0.002 0.08 [0.02–0.40], 0.002
  1. DFS disease-free survival; HR hazard ratio; OS overall survival; CI confidence interval; FIGO International Federation of Gynecology and Obstetrics; AD adenocarcinoma; SCC squamous cell carcinoma; LN lymph node; PM parametrium