Table 1 Patients chracteristics and outcomes
Characteristics | No. of patients (%) | No. of relapse (%) |
|---|---|---|
Number of patients | 152 | 34 (22.4) |
Median age, years (range) | 23 (2–55) | 18.5 (2–55) |
Sex (male/female) | 85/67 | 19/15 |
Disease type | ||
 ALL | 83 (54.6) | 23 (67.6) |
 AML | 69 (45.4) | 11 (32.4) |
Disease status before HSCT | ||
 SR | 117 (77.0) | 29 (85.3) |
 HR | 35 (23.0) | 5 (14.7) |
MRD status before HSCT | ||
 MRD− remission | 104 (68.4) | 20 (58.8) |
 MRD+ remission | 43 (28.3) | 12 (35.3) |
 Refractory disease | 5 (3.3) | 2 (5.9) |
HLA-haploidentical related donor (the number of mismatched locus) | ||
 3 | 93 (61.2) | 19 (55.9) |
 2 | 49 (32.2) | 12 (35.3) |
 1 | 10 (6.6) | 3 (8.8) |
Donor-recipient blood type | ||
 Match | 84 (55.2) | 19 (55.9) |
 Minor mismatch | 29 (19.1) | 4 (11.8) |
 Major mismatch | 27 (17.8) | 9 (26.4) |
 Minor + major | 12 (7.9) | 2 (5.9) |
aGVHD | 48 (31.6) | 12 (35.3) |
 >aGVHD II | 8 (5.3) | 2 (5.9) |
cGVHD | 81 (53.3) | 14 (41.2) |
 Extensive cGVHD | 27 (17.8) | 5 (14.7) |
Median follow-up time (days) | 633.5 (112–1369) | 385.5 (112–1369) |
Death (%) | 31 (20.4) | 19 (55.9) |
Transplantation related death (%) | 12 (7.9) | Â |
IFD | 13 (8.6) | 2 (5.9) |
CMV infection | 117 (77.0) | 25 (73.5) |