Fig. 3
From: Planning clinically relevant biomarker validation studies using the “number needed to treat” concept
Contra-Bayes mapping from predictive values to sensitivity and specificity. See text and Table 2 for details. The points labeled A through F correspond to sensitivities and specificities given in Table 2 lines 1 and 2. a Values from Table 2 lines 3 through 6; b, c values from Table 2 lines 7 through 10. c uses NNT axes in place of predictive value axes. An interactive web application “shinyContraBayes” [29] is available, and also embedded in a more comprehensive application “shinyCombinePlots” [30]