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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Effects of vagus nerve stimulation on cognitive functioning in rats with cerebral ischemia reperfusion

Fig. 6

Vagus nerve stimulation (VNS) improves fear memory after middle cerebral artery occlusion and reperfusion (MCAO/R). From day 5 to day 16 post-surgery, rats in the DSP-4+Sham (n = 7), DSP-4+MCAO/R (n = 13), and DSP-4+MCAO/R+VNS (n = 8) groups were tested in shuttle boxes and the avoidance-conditioned response rates (a), duration of shocks (b), and avoidance latencies were recorded (c). *Indicates a significant difference between the DSP-4+MCAO/R and Sham groups and #Indicates a significant difference between the DSP-4+MCAO/R+VNS and DSP-4+Sham groups. There was no difference between the DSP+MCAO/R and DSP-4+MCAO/R+VNS groups

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