Table 3 Correlations of the expression of miR-7, miR-93, miR-141, miR-195, miR-494, and let-7b with the clinicopathologic characteristics of 104 patients with UICC¹ stage II–III colorectal cancer

Sex

61/38

0.900

64/40

0.193

64/39

0.832

63/40

0.235

63/40

0.483

57/38

0.401

Male

−0.66 ± 0.73

1.70 ± 0.66

0.18 ± 0.68

0.41 ± 0.47

1.98 ± 1.18

2.40 ± 0.65

Female

−0.68 ± 0.70

1.54 ± 0.62

0.21 ± 0.75

0.28 ± 0.63

2.15 ± 1.23

2.27 ± 0.73

Age

60/39

0.427

62/42

0.266

62/41

0.663

62/41

0.074

62/41

0.651

55/40

0.005

≥65 years

−0.71 ± 0.69

1.59 ± 0.70

0.17 ± 0.68

0.29 ± 0.57

2.00 ± 1.28

2.19 ± 0.68

<65 years

−0.60 ± 0.76

1.72 ± 0.55

0.23 ± 0.47

0.47 ± 0.47

2.11 ± 1.28

2.57 ± 0.62

UICC Stage

51/48

0.053

54/50

0.029

54/49

0.954

50/53

0.056

49/54

0.032

46/49

0.419

II

−0.53 ± 0.69

1.77 ± 0.66

0.19 ± 0.72

0.46 ± 0.57

2.28 ± 1.20

2.40 ± 0.70

III

−0.81 ± 0.72

1.50 ± 0.61

0.20 ± 0.69

0.26 ± 0.48

1.88 ± 1.14

2.29 ± 0.70

Maximum size

48/51

0.500

51/53

0.856

50/53

0.407

50/53

0.234

50/53

0.400

49/46

0.854

≥5 cm

−0.62 ± 0.74

1.63 ± 0.58

0.13 ± 0.72

0.29 ± 0.59

1.94 ± 1.24

2.34 ± 0.65

<5 cm

−0.72 ± 0.70

1.65 ± 0.71

0.25 ± 0.69

0.42 ± 0.48

2.14 ± 1.15

2.36 ± 0.72

Location

71/28

0.311

76/28

0.075

75/28

0.023

28/75

0.345

27/76

0.001

27/68

0.602

Colon

−0.72 ± 0.72

1.71 ± 0.65

0.09 ± 0.69

0.39 ± 0.57

1.81 ± 1.14

2.37 ± 0.73

Rectum

−0.55 ± 0.70

1.46 ± 0.61

0.49 ± 0.68

0.29 ± 0.45

2.69 ± 1.12

2.30 ± 0.56

Vascular invasion

27/72

0.961

28/76

0.117

27/76

0.497

28/75

0.084

28/75

0.881

25/70

0.072

Yes

−0.68 ± 0.78

1.48 ± 0.60

0.28 ± 0.77

0.21 ± 0.53

2.01 ± 1.22

2.16 ± 0.54

No

−0.67 ± 0.70

1.70 ± 0.66

0.16 ± 0.68

0.42 ± 0.53

2.05 ± 1.20

2.42 ± 0.72

Perineural invasion

26/73

0.006

27/77

0.375

26/77

0.226

27/76

0.457

27/76

0.134

24/71

0.534

Yes

−0.34 ± 0.67

1.55 ± 0.60

0.36 ± 0.84

0.29 ± 0.59

2.35 ± 1.21

2.26 ± 0.82

No

−0.79 ± 0.70

1.67 ± 0.66

0.13 ± 0.65

0.38 ± 0.52

1.94 ± 1.18

2.38 ± 0.82

Lymph node metastasis

51/48

0.053

54/50

0.029

54/49

0.954

50/53

0.056

49/54

0.032

46/49

0.419

No

−0.53 ± 0.69

1.77 ± 0.66

0.19 ± 0.72

0.46 ± 0.57

2.28 ± 1.20

2.40 ± 0.70

Yes

−0.81 ± 0.72

1.50 ± 0.61

0.20 ± 0.69

0.26 ± 0.48

1.88 ± 1.14

2.29 ± 0.70

Type

89/10

0.440

94/10

0.350

93/10

0.754

93/10

0.480

94/9

0.627

86/9

0.122

Adenocarcinoma

−0.65 ± 0.72

1.66 ± 0.64

0.18 ± 0.72

0.35 ± 0.54

2.03 ± 1.22

2.39 ± 0.67

Mucinous carcinoma

−0.83 ± 0.67

1.44 ± 0.71

0.25 ± 0.58

0.47 ± 0.50

2.20 ± 0.96

1.98 ± 0.68