Fig. 4

Receiver-operating characteristic (ROC) curves of the six individual miRs and the 6-miR panel of all 104 individuals. a ROC curves of the six candidate miRs of all 104 individuals. The sensitivity on the y-axis was plotted against the false-positive fraction (1−specificity) on the x-axis for various cut-off values. b From the ROC plots of miR panel (miR-7, miR-93, miR-141, miR-195, miR-494 and let-7b) expression, two was selected as the cut-off value for detecting early relapsed CRC. The plot is highlighted, with the figures in parentheses indicating sensitivity and specificity. The area under the ROC curve is 0.834 (95 % confidence interval = 0.740–0.905). c From the ROC plots of combine panel expression, four were selected as the cut-off value for detecting early relapsed CRC. The plot is highlighted, with the figures in parentheses indicating sensitivity and specificity. The area under the ROC curve is 0.948 (95 % confidence interval = 0.881–0.984)