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Table 1 Animal characteristics at the end of experiment, according to study group (n = 5–6 per group)

From: Early administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagy

Characteristic

Control

Diabetes mellitus

Diabetes mellitus + trimetazidine

Body weight (g)

434.17 ± 8.60

470.17 ± 27.874

433.67 ± 7.893

Heart weight (mg)

1096.00 ± 35.86

1463.33 ± 37.83*

1293.86 ± 47.94**

Water intake (mL/day)

28.20 ± 3.455

153.83 ± 10.329*

147.00 ± 10.440

Food intake (g/day)

14.44 ± 0.423

29.95 ± 1.090*

29.00 ± 1.163

Urine volume (mL/day)

22.60 ± 2.502

126.33 ± 7.766*

129.00 ± 10.416

Systolic blood pressure (mm Hg)

123.40 ± 4.490

120.67 ± 3.964

116.40 ± 5.609

Diastolic blood pressure (mm Hg)

89.00 ± 4.025

77.17 ± 4.888

84.20 ± 2.354

Mean pressure (mm Hg)

103.80 ± 5.229

90.33 ± 5.245

94.80 ± 3.089

Heart rate (bpm)

454.20 ± 15.714

491.67 ± 13.601

343.20 ± 14.235**

  1. Values are mean ± SEM. bpm, beats per minute
  2. *p < 0.05 compared with control group; and **p < 0.05 compared with diabetes group