Table 6 Multivariate analysis of breast cancer survival

T stage

 T1 versus T2–3

2.376

1.064–5.305

0.035

1.714

0.826–3.556

0.148

N stage

 N0 versus N1–3

2.994

1.424–6.296

0.004

2.127

1.061–4.262

0.033

Histologic grade

 I/II versus III

1.214

0.515–2.859

0.658

0.785

0.353–1.747

0.553

ER status

 Negative versus positive

0.544

0.197–1.507

0.242

0.650

0.259–1.632

0.359

PR status

 Negative versus positive

0.768

0.275–2.147

0.615

0.436

0.164–1.158

0.096

HER-2 status

 Negative versus positive

0.967

0.406–2.307

0.940

1.050

0.463–2.381

0.907

Ki-67 LI

 ≤14 versus >14

0.764

0.308–1.899

0.563

0.805

0.340–1.901

0.620

5-meC (T)

 Low versus high

3.117

0.728–13.35

0.126

1.828

0.543–6.155

0.330

5-meC (S)

 Low versus high

1.498

0.201–11.13

0.693

1.515

0.203–11.31

0.686

DNMT1 (T)

 Low versus high

0.937

0.289–3.037

0.913

1.473

0.538–4.036

0.451

DNMT1 (S)

 Negative versus positive

N/A

N/A

N/A

N/A

N/A

N/A

ISL-1 (T)

 Negative versus positive

N/A

N/A

N/A

2.075

0.270–15.96

0.483