Table 1 Summary of the candidate gene single nucleotide polymorphisms involved in the apoptosis pathway
Gene | Gene description | Chromosome | SNP ID | Allele (m/M) | Call rate (%) | MAF | HWE p value |
|---|---|---|---|---|---|---|---|
APAF1 | Apoptotic peptidase activating factor 1 | 12 | rs1439123 | C/T (Intron) | 100 | 0.04 | 1.00 |
12 | rs2288713 | G/T (Intron) | 100 | 0.27 | 0.71 | ||
CASP10 | Caspase 10, apoptosis-related cysteine peptidase | 2 | rs13006529 | A/T (Leu → Ile) | 100 | 0.18 | 1.00 |
FASLG | Fas ligand (TNF receptor superfamily member 6) | 1 | rs763110 | T/C | 98.4 | 0.29 | 0.98 |
FAS | Fas cell surface death receptor | 10 | rs1800682 | T/C (Intron) | 93.6 | 0.48 | 0.002 |
10 | rs2229521 | G/A(Thr → Thr) | 100 | 0.01 | 1.00 | ||
10 | rs2234767 | A/G (Ala → Thr) | 100 | 0.47 | 0.02 | ||
10 | rs2234978 | T/C (Thr → Thr) | 99.5 | 0.02 | 1.00 |