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Table 1 Summary of the candidate gene single nucleotide polymorphisms involved in the apoptosis pathway

From: Single nucleotide polymorphisms in apoptosis pathway are associated with response to imatinib therapy in chronic myeloid leukemia

Gene Gene description Chromosome SNP ID Allele (m/M) Call rate (%) MAF HWE p value
APAF1 Apoptotic peptidase activating factor 1 12 rs1439123 C/T (Intron) 100 0.04 1.00
12 rs2288713 G/T (Intron) 100 0.27 0.71
CASP10 Caspase 10, apoptosis-related cysteine peptidase 2 rs13006529 A/T (Leu → Ile) 100 0.18 1.00
FASLG Fas ligand (TNF receptor superfamily member 6) 1 rs763110 T/C 98.4 0.29 0.98
FAS Fas cell surface death receptor 10 rs1800682 T/C (Intron) 93.6 0.48 0.002
10 rs2229521 G/A(Thr → Thr) 100 0.01 1.00
10 rs2234767 A/G (Ala → Thr) 100 0.47 0.02
10 rs2234978 T/C (Thr → Thr) 99.5 0.02 1.00
  1. m minor allele, M major allele, MAF minor allele frequency, HWE Hardy–Weinberg equilibrium