Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease

Table 3 Risk estimation of SNPs by ordinal logistic regression analysis in healthy controls, T2D patients, T2D&CAD patients^a

SNP	Group	Estimate	Wald value	p value^b	OR (95 % CI)
rs174537G>T	GG	0.567	6.576	0.010	1.763 (1.143–2.718)
rs174537G>T	GT	0.299	2.145	0.143	1.349 (0.904–2.014)
rs174616C>T	CC	0.256	0.932	0.334	1.292 (0.768–2.175)
rs174616C>T	CT	−0.143	0.285	0.593	0.867 (0.513–1.464)
rs174450A>C	AA	0.054	0.052	0.820	1.055 (0.663–1.680)
rs174450A>C	AC	0.006	0.001	0.978	1.006 (0.637–1.590)
rs174460C>T	TT	0.336	1.388	0.239	1.399 (0.800–2.447)
rs174460C>T	TC	−0.162	1.006	0.316	0.850 (0.619–1.168)

^aOrdinal values were 1 for healthy controls, 2 for patients with T2D, and 3 for patients with T2D&CAD
^b p values derived from ordinal logistic regression after adjustment for sex, age, TC, TG, HDL-cholesterol, LDL-cholesterol, and FPG

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