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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma

Fig. 6

WB analysis of proteins modulated by EXO/miR-222 in Me1007 and Me1402/R melanomas. a Western blot analysis of PI3K/p85β subunit in Tween control vs miR-222-transduced cells and corresponding EXOs (left panel) and relative densitometric quantification (right panel). b Western blot analysis of PI3K/AKT related proteins after fusion of either EXO/Tween or EXO/miR-222 with Tween-transduced melanomas. β-Actin was utilized as internal loading control. c Quantification of ph-AKTSer473/Akt ratios. Mean ± SD of three independent experiments *p < 0.05

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