Fig. 4
From: Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma
In vitro functional studies in Me1007 and Me1402/R. a Morphological and b quantitative analyses of tube formation and length in Tween- and miR-222-transduced melanoma cells compared with EXO/Tween or EXO/miR-222 fused Me1007 or Me1402/R cells. Purified exosomes were incubated with recipient cells for 30 min at 37 °C before performing functional assays. Tube formation was analyzed 20 h after exosome internalization. Data are representative of three independent experiments. *p < 0.05; **p < 0.01