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Table 2 Probability (95 % CI) of no metastasis as a function of time

From: Gene expression identifies heterogeneity of metastatic behavior among gastrointestinal stromal tumors

Time (years) 2 4 6 8 HR
A. Four sample subsets defined by Miettinen risk score (Fig. 3a, p < 0.001)
High risk, n = 17 0.53 (0.34–0.83) 0.28 (0.12–0.68) 0.28 (0.12–0.68) 0.28 (0.12–0.68) 3.4 (1.1, 10.9)
Intermediate risk, n = 14 0.93 (0.80–1.00) 0.85 (0.68–1.00) 0.68 (0.42–1.00) 0.68 (0.42–1.00) Reference group
Low risk, n = 16 NR NR NR No follow-up Not estimable
Very low risk, n = 13 NR NR NR NR Not estimable
B. Two sample subsets among the high- and intermediate-risk samples defined by the AF-gene set in Fig. 1a (Fig. 3b, p = 0.01)
Good group, n = 8 NR NR No follow-up No follow-up Reference group
Bad group, n = 23 0.61 (0.44–0.85) 0.39 (0.22–0.68) 0.32 (0.17–0.63) 0.32 (0.17–0.63) Not estimable
C. Two sample subsets among the high- and intermediate-risk samples defined by the OVCA-gene set in Fig. 1B (Fig. 3C, p < 0.001)
Good group, n = 14 NR 0.93 (0.80–1.00) 0.93 (0.80–1.00) 0.93 (0.80–1.00) Reference group
Bad group, n = 17 0.47 (0.28-0.78) 0.20 (0.06–0.63) 0.10 (0.02–0.61) 0.10 (0.02–0.61) 19.9 (2.6–154.0)
D. Two sample subsets among the high- and intermediate-risk samples defined by the RCC-gene set in Fig. 1c (Fig. 3d, p = 0.045)
Good group, n = 17 0.59 (0.40–0.88) 0.38 (0.20–0.72) 0.28 (0.12–0.67) 0.28 (0.12–0.67) 3.4 (1.0, 12.3)
Bad group, n = 14 0.86 (0.69–1.00) 0.78 (0.59–1.00) No follow-up No follow-up Reference group
E. Two sample subsets among the high- and intermediate-risk samples defined by the combined gene set in Fig. 1d (Fig. 3e, p = 0.06129).
Good group, n = 5 NR NR No follow-up No follow-up Reference group
Bad group, n = 26 0.65 (0.49–0.87) 0.46 (0.29–0.72) 0.38 (0.21–0.68) 0.38 (0.21–0.68) Not estimable
  1. NR no recurrence, HR hazard ratio, NE hazard ratio can not be estimated when one group has no events