Fig. 3

Kaplan–Meier analysis of the time to development of metastases. Kaplan–Meier analysis of the time to development of metastases for Miettinen risk groups of all GIST samples (a). Miettinen risk identified distinct risk groups (p < 0.001), panel a. When the 31 high- and intermediate-risk GIST samples from panel a were examined for their grouping using the individual AF-gene set (b), OVCA-gene set (c), RCC-gene set (d), and the combined gene set (e) in Fig. 1, the time to development of metastasis differed between groups A and B (b, p < 0.001; c, p = 0.003; d, p = 0.029; and e, p = 0.029)