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Table 1 Demographic and clinical-pathologic characteristics of study cohorts

From: A multiplex immunoassay for the non-invasive detection of bladder cancer

 

Cohort #1

P value*

Cohort #2

P value*

Bladder cancera (n = 29)

Benignb and healthy controls (n = 33)

Bladder cancera (n = 100)

Benignb and healthy controls (n = 100)

Median age (range, years)

68 (51, 93)

50 (20, 81)

<0.0001

70 (20, 89)

50.5 (18, 81)

<0.0001

Male:female ratio

25:4

27:6

0.639

81:18

81:19

0.882

Clinical stage and grade

 Tis high-grade

3 (10.3 %)

  

4 (4.0 %)

  

 Ta low-grade

4 (13.8 %)

  

17 (17.0 %)

  

 Ta high-grade

6 (20.7 %)

  

11 (11.0 %)

  

 T1 low-grade

0 (0 %)

  

4 (4.0 %)

  

 T1 high-grade

3 (10.3 %)

  

22 (22.0 %)

  

 ≥T2 high-grade

13 (44.8 %)

  

42 (42.0 %)

  
  1. * Wilcoxon rank sum test
  2. aPrimary BCa; no patient with a history of BCa
  3. bVoiding symptoms, microscopic hematuria