Fig. 5

miR-483-3p and SRF functionally regulate EPCs function. a Decreased EPCs migration in EPCs transfected with SRF-siRNA. (n = 3, **P < 0.01 vs. negative control; ^##P < 0.01 vs. miR-483-3p agomir + SRF). b Decreased tube number and length in EPCs transfected with SRF-siRNA (×100) (n = 3, **P < 0.01vs NC; ^##P < 0.01 vs. miR-483-3p agomir + SRF). c Increased EPCs apoptosis after SRF-siRNA transfection. (n = 3, *P < 0.05 vs. negative control; **P < 0.01 vs. negative control; ^##P < 0.01 vs. miR-483-3p agomir + SRF). Each bar represents mean values ± SEM