Fig. 1

Somatic copy number amplifications (red), deletions (green), or neutral (yellow) identified in the primary (inner track) and recurrent (outer track) tumors of a HCC1, b HCC4, c HCC5, and d HCC11; e both shared and unique regions of CN amplifications or deletions in 3/4 patients across the genome. Color code is as follows: unique to primary tumors (red amplification; blue deletion); unique to recurrent tumors (brown amplification); and shared by the primary and recurrent tumors (green amplification; purple deletion)