Fig. 4

Clotting time (in minutes) induced by the different investigated wound pads and a control without specimen application. Results were assessed via spectrophotometric extinction measurement of thrombin activity. a Healthy volunteers, b Marcumar^® patients, c ASS^® patients, d summarized graphic depiction of all groups (statistics not reported). Values are expressed as means ± STD. (*p < 0.05 vs. control; ^# p < 0.05 vs. standard wound pad; °p < 0.05 vs. alginate-d; ^● p < 0.05 vs. oxidized cellulose; ^ϫp < 0.05 vs. Lyostypt^®)