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Table 2 mRNA expression of different genes involved in de novo lipogenesis in human visceral adipose tissue

From: Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue

  Non-obese
subjects
(N = 15)
MO-low-IR subjects
(N = 15)
MO-high-IR subjects
(N = 15)
SIRT3 0.029 ± 0.014 0.021 ± 0.015 0.009 ± 0.006a*
PDHB 0.460 ± 0.170 0.244 ± 0.066a 0.248 ± 0.081a
ACC1 1.87 ± 0.43 1.15 ± 0.52a 0.91 ± 0.59a
ACSS2 1.14 ± 0.29 0.78 ± 0.42a 0.80 ± 0.39a
ACLY 1.01 ± 0.79 0.42 ± 0.08a 0.31 ± 0.06a
PPARγ 1.12 ± 0.65 2.72 ± 1.89a 2.51 ± 0.87a
SREBP-1c 0.271 ± 0.172 0.131 ± 0.072a 0.116 ± 0.067a
FASN 0.285 ± 0.088 0.148 ± 0.040a 0.124 ± 0.020a
  1. MO-low-IR morbidly obese subjects with low insulin resistance, MO-high-IR morbidly obese subjects with high insulin resistance
  2. aP < 0.05 significant differences with respect to the non-obese group
  3. * P < 0.05 significant differences between morbidly obese patients with low and high insulin resistance. All significant differences are adjusted for sex