Fig. 8

Tumor development was suppressed by β-elemene in nude mice transplanted with glioblastoma cells. Nude mice transplanted with glioblastoma cells received an intraperitoneal injection of NaCl or 50 mg/kg β-elemene for 1 week, and the tumor volumes were measured every 3 days. a In contrast with the NaCl-treated group, a remarkable suppression of tumor growth was detected from day 9 after transplantation (day 3 after intraperitoneal injection) to day 21 in the β-elemene-treated group of G1, G2 or U87 cell-transplanted nude mice. b, c The tumor weights in the β-elemene group on day 21 after transplantation were significantly less than those of the NaCl group. The values are presented as the mean ± SD (*p < 0.05, **p < 0.01)