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Table 1 Biospecimens: collection tube and volume, material, parameters, and destination

From: The Cooperative Health Research in South Tyrol (CHRIS) study: rationale, objectives, and preliminary results

Collection tube type

Volume collected (ml)

Assay material

Purpose

Blood/Urine Analyses

Biobank

Parameter

No. of Aliquots

Aliquot volume (µl)

Storage temp. (°C)

Serum gel + Clot Act. Venosafe VF108SAS

16

Serum

Antinuclear antibodies; Albumin; CRP; Calcium; Chlorine; Potassium; Magnesium; Sodium; Phosphorous; Ferritin; Iron; Transferrin; Creatinine; Uric acid; Cholesterol; HDL; LDL; Triglycerides; Lipase; Direct and total bilirubin; GGT; AST; GOT; ALT; GPT; ALP; Cortisol; Glucose; anti-TPO AB; TSH; FT4 and FT3 in case of abnormal TSH

15

220

–80

K2-EDTA Venosafe VF053SDK

15

EDTA plasma

Monocytes; Basophils; Neutrophils; Lymphocytes; Eosinophils; HCT; HGB; Mean Red Blood Cell; MCH; MCHC; MCV; MPV; RDW; PLT; RBC; WBC; HbA1c

10

220

–80

EDTA buffy coat in RNA later

/

4

490

–80

DNA

/

2

Variable

–20

Na3-Citrate Buffered Venosafe VF054SBCS07

14.5

Citrate plasma

Antithrombin; Fibrinogen; INR; PT; aPTT

10

220

–80

Citrate buffy coat +DMSO

/

1

900

–190

Citrate whole blood + DMSO

/

3

1000

–190

Gel + Li.Heparin. Venosafe VF054SAHLAS

3.5

Heparin plasma

Homocysteine

/

/

/

Vacutest U218007/U14930

30

Urine

pH; Glucose; Proteins; Haemoglobin; Ketone bodies; Bilirubin; Urobilinogen; Specific weight; Nitrites; Leukocytes-esterase; Leukocytes; Erythrocytes; Epithelial cells; Bacteria; Creatinine; Albumin; ACR

15

220

–80

  1. CRP C-reactive protein, HDL high density lipoprotein, LDL low density lipoprotein, GGT gamma-glutamyl transferase, AST aspartate aminotransferase, GOT glutamic oxaloacetic transaminase, ALT alanine aminotransferase, GPT glutamate pyruvate transaminase, ALP alkaline phosphatase, anti-TPO AB anti-thyroid peroxidase antibodies, TSH thyroid-stimulating hormone reflex, FT4 free thyroxine, FT3 free triiodothyronine, HCT haematocrit, HGB haemoglobin, MCH mean cell haemoglobin, MCHC mean red blood cell haemoglobin concentration, MCV mean red blood cell volume, MPV mean platelet volume, RDW red blood cell distribution width, PLT platelet count, RBC red blood cell count, WBC white blood cell count, HbA1c glycated hemoglobin, INR international normalized ratio, PT prothrombin time, aPTT activated partial thromboplastin time, ACR albumin-to-creatinine ratio