Higher heat shock factor 1 expression in tumor stroma predicts poor prognosis in esophageal squamous cell carcinoma patients

Table 2 Clinicpathological associations of HSF-1 expression levels in 134 patients with ESCC

Clinicopathologic parameter	Total case (n = 134)	High level of HSF-1 in tumor (%)	P	High level of HSF-1 in stromal (%)	P
Age (years)
≤61	67	37 (55.2)	0.727	36 (53.7)	0.486
>61	67	39 (58.2)	0.727	40 (59.7)	0.486
Gender
Female	26	11 (42.3)	0.099	10 (38.5)	0.036*
Male	108	65 (60.2)	0.099	66 (61.1)	0.036*
Degree of differentiation
G1	42	18 (42.9)	0.082	17 (40.5)	0.021*
G2	57	37 (64.9)		39 (68.4)
G3	35	21 (60.0)		20 (57.1)
T status
T1–2	48	15 (31.2)	<0.001*	15 (31.2)	<0.001*
T3–4	86	61 (70.9)	<0.001*	61 (70.9)	<0.001*
N status
N0	65	29 (44.6)	0.006*	28 (43.1)	0.002*
N1	69	47 (68.1)	0.006*	48 (69.6)	0.002*
M status
M0	128	73 (57.0)	1.000	72 (56.2)	0.935
M1	6	3 (50.0)	1.000	4 (66.7)	0.935
Clinical stage
I–II	72	32 (44.4)	0.002*	33 (45.8)	0.006*
III–IV	62	44 (71.0)	0.002*	43 (69.4)	0.006*

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