Fig. 4

CHBP inhibited TGF-β-induced EMT in murine and human TECs. TGF-β (5 ng/ml) and CHBP (0, 0.1, 1 and 10 μM) were added to murine TCMK-1 and human HK-2 cells. After 72 h, E-cadherin, vimentin and α-SMA levels in a TCMK-1 cells and b HK-2 cells were determined by western blotting. c, d Quantitative results are presented as the mean ± SD of the optical density of each band (n = 6). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared with the CHBP (0 μM) + TGF-β (5 ng/ml) group