Fig. 5

a Pulmonary inflammatory cell infiltrate at different time-points after the beginning of DRA in the absence or presence of budesonide treatment beginning after 4 weeks of DRA. Eight mice were used for every time points and the experiment was replicated three times. Score values, determined as described in "Methods", are expressed as mean ± SEM of the three different experiments. The dashed line represents the average value of control animals treated with saline. b Airway epithelium hypertrophy at different time-points after the beginning of DRA in the absence or presence of budesonide treatment beginning after 4 weeks of DRA. Eight mice were used for every time points and the experiment was replicated three times. Score values, determined as described in "Methods", are expressed as mean ± SEM of the three different experiments. c Goblet cells quantitation at different time-points after the beginning of DRA in the absence or presence of budesonide treatment beginning after 4 weeks of DRA. Eight mice were used for every time points and the experiment was replicated three times. Score values, determined as described in “Methods”, are expressed as mean ± SEM of the three different experiments. The dashed line represents the average value of control animals treated with saline. Statistical analysis was carried out by one-way ANOVA followed by Fischer’s exact test. P < 0.05 and **P < 0.01