Fig. 1

Overview of the experimental groups and type and grade of hepatic fat content. To induce hepatic steatosis, mice received the choline-deficient l-amino acid-defined (CD-AA) diet for 3, 8, and 20 weeks. The control mice were fed with choline-sufficient l-amino acid defined (CS-AA) chow diet for the same time periods. The ob/ob (leptin deficient) mice and their lean controls received the standard chow diet for 4 weeks. After the specific weeks of diet, DRS measurements were performed in liver tissue ex vivo