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Table 3 Differentiating serum proteins

From: Identification of serum proteome signatures of locally advanced and metastatic gastric cancer: a pilot study

Protein name

Protein full name

Gene name

Control/cancer

Local/metastatic

Ratio

p value

Ratio

p value

A1AG1

Alpha-1-acid glycoprotein 1

ORM1

0.67

0.0008

1.00

0.5824

A1AG2

Alpha-1-acid glycoprotein 2

ORM2

0.68

0.0006

1.00

0.7414

A1AT

Alpha-1-antitrypsin

SERPINA1

0.50

<0.0001

1.03

0.6441

A1BG

Alpha-1B-glycoprotein

A1BG

0.76

0.0072

1.04

0.5824

A2GL

Leucine-rich alpha-2-glycoprotein

LRG1

0.46

0.0016

0.80

0.4414

AACT

Alpha-1-antichymotrypsin

SERPINA3

0.54

0.0007

0.97

0.9124

ADIPO

Adiponectin

ADIPOQ

0.41

0.0092

1.60

0.3442

AFAM

Afamin

AFM

1.30

0.0355

1.06

0.5824

ANGI

Angiogenin

ANG

0.30

0.0465

0.24

0.0294

APOA1

Apolipoprotein A-I

APOA1

0.47

<0.0001

1.31

0.0235

APOC1

Apolipoprotein C-I

APOC1

0.25

<0.0001

1.52

0.1183

APOC3

Apolipoprotein C-III

APOC3

1.82

0.0108

1.20

0.5824

APOE

Apolipoprotein E

APOE

0.62

0.0040

1.01

0.6441

APOF

Apolipoprotein F

APOF

0.64

0.0085

0.80

0.5235

APOM

Apolipoprotein M

APOM

0.92

0.4275

1.51

0.0263

C1S

Complement C1s subcomponent

C1S

0.70

0.0016

1.22

0.0748

CAH1

Carbonic anhydrase 1

CA1

2.96

0.0173

2.41

0.0143

CBG

Corticosteroid-binding globulin

SERPINA6

0.53

0.0117

1.08

0.7749

CD14

Monocyte antigen CD14

CD14

0.56

0.0033

1.21

0.1658

CERU

Ceruloplasmin

CP

0.67

0.0013

1.05

0.6129

CFAB

Complement factor B

CFB

0.61

0.0006

1.11

0.6441

CO2

Complement C2

C2

0.64

0.0475

1.57

0.0679

CO4A

Complement C4-A

C4A

0.87

0.0435

0.94

0.7749

CO4B

Complement C4-B

C4B

0.73

0.0127

0.99

0.5526

CO5

Complement C5

C5

0.77

0.0085

0.91

0.8776

CO6

Complement component C6

C6

0.64

0.0013

0.97

0.8431

CO8G

Complement component C8 gamma

C8G

0.66

0.0137

1.12

0.4679

CO9

Complement component C9

C9

0.42

<0.0001

0.93

0.9124

CRP

C-reactive protein

CRP

<0.01

0.0389

0.15

0.0414

CXCL7

Platelet basic protein

PPBP

0.83

0.1516

1.53

0.0030

FETUA

Alpha-2-HS-glycoprotein

AHSG

0.90

0.3095

1.34

0.0068

FHR1

Complement factor H-related prot. 1

CFHR1

0.66

0.0725

1.30

0.0366

GPX3

Glutathione peroxidase 3

GPX3

0.92

0.6065

1.47

0.0453

HBA

Hemoglobin subunit alpha

HBA1

2.02

0.0016

1.18

0.5824

HBB

Hemoglobin subunit beta

HBB

2.26

0.0005

1.11

0.6441

HBD

Hemoglobin subunit delta

HBD

4.59

0.0030

1.02

0.9608

HEMO

Hemopexin

HPX

0.77

0.0061

1.00

0.9124

HGFA

Hepatocyte growth factor activator

HGFAC

1.57

0.0868

1.74

0.0366

HGFL

Hepatocyte growth factor-like prot.

MST1

1.40

0.4048

3.28

0.0156

HPT

Haptoglobin

HP

0.68

0.0014

1.02

0.7749

IC1

Plasma protease C1 inhibitor

SERPING1

3.36

0.0001

0.21

0.0030

ITIH1

Inter-alpha-trypsin inhib. heavy ch. 1

ITIH1

0.77

0.0465

1.06

0.2099

ITIH3

Inter-alpha-trypsin inhib. heavy ch. 3

ITIH3

0.45

0.0001

1.05

0.4414

LBP

Lipopolysaccharide-binding protein

LBP

0.42

0.0004

0.78

0.7084

LG3BP

Galectin-3-binding protein

LGALS3BP

0.23

0.0006

1.29

0.8776

PGRP2

N-acetylmuramoyl-l-alanine amidase

PGLYRP2

0.82

0.0497

1.15

0.4157

PLF4

Platelet factor 4

PF4

1.00

0.9667

1.41

0.0366

PON1

Serum paraoxonase/arylesterase 1

PON1

0.88

0.4606

1.42

0.0442

PROP

Properdin

CFP

1.45

0.0028

1.11

0.9825

PROZ

Vitamin K-dependent protein Z

PROZ

0.93

0.6864

2.08

0.0186

S10A9

Protein S100-A9

S100A9

0.11

0.0054

0.74

0.2526

SAA1

Serum amyloid A-1 protein

SAA1

0.04

0.0407

0.49

0.2099

SAA2

Serum amyloid A-2 protein

SAA2

<0.01

0.0389

0.44

0.3069

SEPP1

Selenoprotein P

SEPP1

1.72

0.1292

1.52

0.0186

SHBG

Sex hormone-binding globulin

SHBG

0.20

0.0329

0.67

0.1968

THBG

Thyroxine-binding globulin

SERPINA7

0.70

0.0309

0.80

0.8088

TSP1

Thrombospondin-1

THBS1

0.74

0.1363

1.49

0.0436

VTDB

Vitamin D-binding protein

GC

0.81

0.0160

1.24

0.0235

VTNC

Vitronectin

VTN

0.82

0.0394

1.15

0.1083

  1. Showed are proteins, which abundances were different between samples from healthy controls and patients with stomach cancer (all cases), or between patients with locally advanced and metastatic cancer. Differences (ratios of the mean abundances) that passed the threshold of statistical significance (p < 0.05) are marked in italics characters
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Journal of Translational Medicine

ISSN: 1479-5876

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