Skip to main content

Advertisement

Table 3 Differentiating serum proteins

From: Identification of serum proteome signatures of locally advanced and metastatic gastric cancer: a pilot study

Protein name Protein full name Gene name Control/cancer Local/metastatic
Ratio p value Ratio p value
A1AG1 Alpha-1-acid glycoprotein 1 ORM1 0.67 0.0008 1.00 0.5824
A1AG2 Alpha-1-acid glycoprotein 2 ORM2 0.68 0.0006 1.00 0.7414
A1AT Alpha-1-antitrypsin SERPINA1 0.50 <0.0001 1.03 0.6441
A1BG Alpha-1B-glycoprotein A1BG 0.76 0.0072 1.04 0.5824
A2GL Leucine-rich alpha-2-glycoprotein LRG1 0.46 0.0016 0.80 0.4414
AACT Alpha-1-antichymotrypsin SERPINA3 0.54 0.0007 0.97 0.9124
ADIPO Adiponectin ADIPOQ 0.41 0.0092 1.60 0.3442
AFAM Afamin AFM 1.30 0.0355 1.06 0.5824
ANGI Angiogenin ANG 0.30 0.0465 0.24 0.0294
APOA1 Apolipoprotein A-I APOA1 0.47 <0.0001 1.31 0.0235
APOC1 Apolipoprotein C-I APOC1 0.25 <0.0001 1.52 0.1183
APOC3 Apolipoprotein C-III APOC3 1.82 0.0108 1.20 0.5824
APOE Apolipoprotein E APOE 0.62 0.0040 1.01 0.6441
APOF Apolipoprotein F APOF 0.64 0.0085 0.80 0.5235
APOM Apolipoprotein M APOM 0.92 0.4275 1.51 0.0263
C1S Complement C1s subcomponent C1S 0.70 0.0016 1.22 0.0748
CAH1 Carbonic anhydrase 1 CA1 2.96 0.0173 2.41 0.0143
CBG Corticosteroid-binding globulin SERPINA6 0.53 0.0117 1.08 0.7749
CD14 Monocyte antigen CD14 CD14 0.56 0.0033 1.21 0.1658
CERU Ceruloplasmin CP 0.67 0.0013 1.05 0.6129
CFAB Complement factor B CFB 0.61 0.0006 1.11 0.6441
CO2 Complement C2 C2 0.64 0.0475 1.57 0.0679
CO4A Complement C4-A C4A 0.87 0.0435 0.94 0.7749
CO4B Complement C4-B C4B 0.73 0.0127 0.99 0.5526
CO5 Complement C5 C5 0.77 0.0085 0.91 0.8776
CO6 Complement component C6 C6 0.64 0.0013 0.97 0.8431
CO8G Complement component C8 gamma C8G 0.66 0.0137 1.12 0.4679
CO9 Complement component C9 C9 0.42 <0.0001 0.93 0.9124
CRP C-reactive protein CRP <0.01 0.0389 0.15 0.0414
CXCL7 Platelet basic protein PPBP 0.83 0.1516 1.53 0.0030
FETUA Alpha-2-HS-glycoprotein AHSG 0.90 0.3095 1.34 0.0068
FHR1 Complement factor H-related prot. 1 CFHR1 0.66 0.0725 1.30 0.0366
GPX3 Glutathione peroxidase 3 GPX3 0.92 0.6065 1.47 0.0453
HBA Hemoglobin subunit alpha HBA1 2.02 0.0016 1.18 0.5824
HBB Hemoglobin subunit beta HBB 2.26 0.0005 1.11 0.6441
HBD Hemoglobin subunit delta HBD 4.59 0.0030 1.02 0.9608
HEMO Hemopexin HPX 0.77 0.0061 1.00 0.9124
HGFA Hepatocyte growth factor activator HGFAC 1.57 0.0868 1.74 0.0366
HGFL Hepatocyte growth factor-like prot. MST1 1.40 0.4048 3.28 0.0156
HPT Haptoglobin HP 0.68 0.0014 1.02 0.7749
IC1 Plasma protease C1 inhibitor SERPING1 3.36 0.0001 0.21 0.0030
ITIH1 Inter-alpha-trypsin inhib. heavy ch. 1 ITIH1 0.77 0.0465 1.06 0.2099
ITIH3 Inter-alpha-trypsin inhib. heavy ch. 3 ITIH3 0.45 0.0001 1.05 0.4414
LBP Lipopolysaccharide-binding protein LBP 0.42 0.0004 0.78 0.7084
LG3BP Galectin-3-binding protein LGALS3BP 0.23 0.0006 1.29 0.8776
PGRP2 N-acetylmuramoyl-l-alanine amidase PGLYRP2 0.82 0.0497 1.15 0.4157
PLF4 Platelet factor 4 PF4 1.00 0.9667 1.41 0.0366
PON1 Serum paraoxonase/arylesterase 1 PON1 0.88 0.4606 1.42 0.0442
PROP Properdin CFP 1.45 0.0028 1.11 0.9825
PROZ Vitamin K-dependent protein Z PROZ 0.93 0.6864 2.08 0.0186
S10A9 Protein S100-A9 S100A9 0.11 0.0054 0.74 0.2526
SAA1 Serum amyloid A-1 protein SAA1 0.04 0.0407 0.49 0.2099
SAA2 Serum amyloid A-2 protein SAA2 <0.01 0.0389 0.44 0.3069
SEPP1 Selenoprotein P SEPP1 1.72 0.1292 1.52 0.0186
SHBG Sex hormone-binding globulin SHBG 0.20 0.0329 0.67 0.1968
THBG Thyroxine-binding globulin SERPINA7 0.70 0.0309 0.80 0.8088
TSP1 Thrombospondin-1 THBS1 0.74 0.1363 1.49 0.0436
VTDB Vitamin D-binding protein GC 0.81 0.0160 1.24 0.0235
VTNC Vitronectin VTN 0.82 0.0394 1.15 0.1083
  1. Showed are proteins, which abundances were different between samples from healthy controls and patients with stomach cancer (all cases), or between patients with locally advanced and metastatic cancer. Differences (ratios of the mean abundances) that passed the threshold of statistical significance (p < 0.05) are marked in italics characters