Fig. 8

The interplay between HGF receptor, EGFR and YZXJ, as measured by cell migration. a A549 cellular migration tracked by EVOS. Cells were scratch-wounded and then added with YZXJ (1:1000), HGF (50 ng/ml)/EGF (10 ng/ml), the HGFR/EGFR inhibitors (PHA665752 10 nM and AG490 5 µM) alone or in combinations; b Migration distance for A549 cells; c Migration distance for SKMES1 cells. a: p < 0.05 vs no HGF/EGF; b: vs YZXJ alone; c: vs with HGF/EGF alone