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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: YangZheng XiaoJi exerts anti-tumour growth effects by antagonising the effects of HGF and its receptor, cMET, in human lung cancer cells

Fig. 1

Effects of YangZheng XiaoJi on cell migration, adhesion and invasion. a Cell images from A549 wounding model. Left control group in which cell monolayer was wounding and monitored continuously for 8 h. Right DME25 treated group, similarly wounded and monitored. DME25 dilution used was 1:1000. b Cellular migration of A549 as tracked by EVOS imaging system and quantified migration speed (in pixels). YangZheng XiaoJi had a significant inhibitory effect on the migration (p < 0.001). c, d YangZheng XiaoJi HGF-induced cell migration (shown are at 6 h after wounding). HGF (shown at 50 ng/ml) had a significant stimulatory effects on cell migration of both A549 (d) (p < 0.05 vs control) and to some degree SKMES1 cells (c) (p = 0.08). YangZheng XiaoJi inhibited HGF-induced cell migration (p < 0.05 vs control, p < 0.05 vs with HGF only). e, f Effects of YangZheng XiaoJi on cell invasion. YangZheng XiaoJi inhibited in vitro invasion of both cells (p < 0.05 vs control)

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Journal of Translational Medicine

ISSN: 1479-5876

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