Correlation of exosome number with ALT, exosomes RNA yield and miRNA assay. a The correlation of exosome number (particle/ml) with ALT level (IU/L) was identified by Spearman's correlation test. b Exosomes were isolated and treated with RNase. The total amount of RNA in the exosome fraction and exosome-depleted serum was compared using a Nanodrop. c Historical values of spiked positive control miRNAs were compared with the assay values. d This graph depicts the miRNAs included in the whole inflammatory panel. Purple color indicates detectable miRNAs in our samples.